CG428-NEG [CAS 2714560-39-9]

CG428-NEG is a TRK degrader negative control. CG428 inhibits cell growth and reduce TPM3-TRKA levels[1].

[2714560-39-9]

C44H45FN10O6

828.89

O=C1N(C(CC2)C(N(C)C2=O)=O)C(C3=C1C=CC=C3NCCOCCC(N4CCN(C5=NC(C6=CN=C7C=CC(N8[C@@H](C9=CC=CC(F)=C9)CCC8)=NN76)=CC=C5)CC4)=O)=O

PROTACs; Trk Receptor

97.6

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice