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CGMP-HTL
CGMP-HTL
SKU:QM-0062394-01
£1,354.91 GBP
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Product Details
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Description
CGMP-HTL contains a HT-ligand, a linker and the Cys-S-cGMP (autophagy tag) . cGMP-HTL increases the K63-linked ubiquitination of mitochondria. AUTAC (autophagy-targeting chimera) is a novel targeted-clearance strategy that contains a degradation tag (guanine derivatives) and a warhead to provide target specificity[1].
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Molecular Formula
C31H51ClN7O14PS
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Molecular Weight
844.27
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Smiles
NC(N1)=NC2=C(N=C(SC[C@H](NC(C)=O)C(NCCOCCOCCOCCOCCOCCCCCCCl)=O)N2[C@H]3[C@H](O)[C@H](OP4(O)=O)[C@@H](CO4)O3)C1=O
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Target
Autophagy
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Purity
99.71
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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CGMP-HTL
CGMP-HTL is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.