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ChE/GSK-3β-IN-1
ChE/GSK-3β-IN-1
SKU:QM-0016063
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Product Details
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Description
ChE/GSK-3β-IN-1 (compound 18o) is a potent dual ChE/GSK-3β inhibitor. ChE/GSK-3β-IN-1 exhibits dual inhibition of AChE (IC50 = 1.7 μM), butyrylcholinesterase (BChE) (IC50 = 5.3 μM), and GSK-3β (IC50 = 5.7 μM) . ChE/GSK-3β-IN-1 inhibits Aβ1-42 self-aggregation. ChE/GSK-3β-IN-1 can be used for Alzheimer’s disease (AD) research[1].
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Molecular Formula
C26H30N4O2
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Molecular Weight
430.54
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Smiles
O=C1CC2=C(C3=CC=CC=C3N1)NC4=C2C=C(C=C4)C(NCCCNC5CCCCC5)=O
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Target
Amyloid-β; Cholinesterase (ChE) ; GSK-3
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Isoform
AChE; BChE; GSK-3β
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Shipping Conditions
Room temperature
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ChE/GSK-3β-IN-1
ChE/GSK-3β-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.