ChEs/MAOs-IN-1

ChEs/MAOs-IN-1 (Compound 4i) is a dual inhibitor of cholinesterases (ChEs) and monoamine oxidases (MAOs) .ChEs/MAOs-IN-1 has IC50 values of 0.048 μM, 0.89 μM, 3.58 μM, and 0.095 μM for AChE, BChE, MAO-B and MAO-B respectively. ChEs/MAOs-IN-1 can be used in the study of neurodegenerative diseases[1].

C15H10Cl2N2O3

337.16

O=C(N/N=C/C1=CC=CC(Cl)=C1Cl)C2=CC(OCO3)=C3C=C2

Monoamine Oxidase

10 mM in DMSO

Room temperature