Chevalone C [CAS 1318025-77-2]

Chevalone C, a meroterpenoid fungal metabolite, shows antimalarial activity with IC50 value of 25.00 μg/mL. Chevalone C has anti-proliferative activity on colon HCT116, liver HepG2 and melanoma A375 cancer cell lines[1][2].

[1318025-77-2]

C28H40O5

456.61

CC(OC1=C2C[C@@]3([C@@](C)(O1)CC[C@]4([C@]3(CC[C@@]5([C@@]4(CC[C@@H](C5(C)C)OC(C)=O)C)[H])C)[H])[H])=CC2=O

Parasite

Plasmodium

10 mM in DMSO

Room temperature