Chloramphenicol [CAS 56-75-7]
Chloramphenicol [CAS 56-75-7]
SKU:QM-0157836-01
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Product Details
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Description
Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research[1][2][3].
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CAS Number
[56-75-7]
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Molecular Formula
C11H12Cl2N2O5
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Molecular Weight
323.13
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Smiles
O=C(N[C@H](CO)[C@H](O)C1=CC=C([N+]([O-])=O)C=C1)C(Cl)Cl
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Target
Akt; Antibiotic; Apoptosis; Autophagy; Bacterial; Beclin1; HIF/HIF Prolyl-Hydroxylase; JNK; MMP; VEGFR
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Isoform
JNK; MMP-13
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Purity
99.96
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Solubility
DMSO : ≥ 150 mg/mL|Ethanol : 100 mg/mL (ultrasonic) |H2O : 3.06 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H318, H351, H361
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Precautions
H318, H351, H361
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Chloramphenicol [CAS 56-75-7]
Chloramphenicol is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.