Chloranil [CAS 118-75-2]

Chloranil (Tetrachloro-p-benzoquinone), an orally active metabolite of pentachlorophenol and hexachlorobenzene, is a widely used fungicide. Chloranil can induce ROS production. Chloranil induces neutrophil extracellular traps through the ROS-JNK-NOX2 pathway. Chloranil induces ferroptosis and neuroinflammation. Chloranil induces apoptosis of mouse embryonic stem cells[1][2][3][4][5] .

[118-75-2]

C6Cl4O2

245.88

O=C1C(Cl)=C(Cl)C(C(Cl)=C1Cl)=O

Apoptosis; Ferroptosis; Fungal; JNK; MyD88; Reactive Oxygen Species (ROS) ; Toll-like Receptor (TLR)

TLR4

99.51

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315, H317, H318, H410

H315, H317, H318, H410