Cholest-5-ene-3ß,22 (S) -diol [CAS 22348-64-7]

Cholest-5-ene-3ß,22 (S) -diol ((22S) -Hydroxycholesterol) is an orally active oxysterol with no significant cytotoxic, oxidative, or inflammatory effects on human prokaryotic leukemia cells. Cholest-5-ene-3ß,22 (S) -diol inhibits weight gain and increased serum triacylglycerol (TAG) levels in rat models[1][2].

[22348-64-7]

C27H46O2

402.65

C[C@]12[C@](CC[C@]1([H])[C@H](C)[C@@H](O)CCC(C)C)([H])[C@@](CC=C3C[C@H]4O)([H])[C@@](CC2)([H])[C@]3(CC4)C

ATP-binding cassette (ABC) transporters; LXR

98.6

10 mM in DMSO

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H302, H315, H319, H335

H302, H315, H319, H335