CHS-111 [CAS 886755-63-1]

CHS-111 is a benzyl indazole inhibitor of superoxide anion O2- generation. CHS-111 inhibits the cell migration, and reduces the formyl-Met-Leu-Phe- but not phorbol ester-stimulated phospholipase D activity, with the IC50 of 3.9 μM[1].

[886755-63-1]

C21H18N2O

314.38

OCC1=CC=C(C=C1)C2=C3C=CC=CC3=NN2CC4=CC=CC=C4

Reactive Oxygen Species (ROS)

10 mM in DMSO

Room temperature