Cilagicin

Cilagicin, a dodeca-lipodepsipeptide, is a Gram-positive active antibiotic. Cilagicin has a dual polyprenyl phosphate binding mechanism that impedes resistance development[1].

C68H103N15O21

1466.63

CCCCCCCCCCCCCC(N[C@H](CO)C(N[C@@H]1C(N[C@H](CCN)C(N[C@@H](CC(O)=O)C(NCC(N[C@H](CC(N)=O)C(N[C@H](CC(O)=O)C(NCC(N[C@@H](CC2=CC=C(O)C=C2)C(N[C@@H](C(C)C)C(N[C@@H](CCN)C(N[C@@H](CC3=CC=CC=C3)C(O[C@@H]1C)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O

Antibiotic; Bacterial

10 mM in DMSO

Room temperature