Cipepofol [CAS 1637741-58-2]

Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol. Cipepofol can activate the sirtuin1 (Sirt1) /Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO; HY-B0468) -induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis[1][2].

[1637741-58-2]

C14H20O

204.31

CC(C1=CC=CC([C@@H](C2CC2)C)=C1O)C

Apoptosis; GABA Receptor; Keap1-Nrf2; Sirtuin

99.82

DMSO : 100 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature