Cis-α- (Carboxycyclopropyl) glycine [CAS 117857-95-1]
Cis-α- (Carboxycyclopropyl) glycine [CAS 117857-95-1]
SKU:QM-0056967
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Product Details
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Description
Cis-α- (Carboxycyclopropyl) glycine (L-CCG III) is a potent, competitive glutamate uptake inhibitor. cis-α- (Carboxycyclopropyl) glycine is a substrate of glutamate transporters (GluT) (EC50: 13 μM, 2 μM for EAAT 1 and EAAT 2, respectively) . cis-α- (Carboxycyclopropyl) glycine inhibits a Na+-dependent high-affinity L-glutamate uptake in glial plasmalemmal vesicles (GPV) and synaptosomes[1][2].
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CAS Number
[117857-95-1]
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Molecular Formula
C6H9NO4
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Molecular Weight
159.14
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Smiles
[H][C@@]1([C@H](N)C(O)=O)[C@H](C(O)=O)C1
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Target
EAAT
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Isoform
EAAT1; EAAT2
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Cis-α- (Carboxycyclopropyl) glycine [CAS 117857-95-1]
Cis-α- (Carboxycyclopropyl) glycine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.