Citronellol-d6 [CAS 220687-53-6]

Citronellol-d6 is deuterated labeled Citronellol. Citronellol ((±) -Citronellol) is an orally active inducer of apoptosis. Citronellol can prevent oxidative stress, mitochondrial dysfunction, and apoptosis in the SH-SY5Y cell Parkinson's disease model induced by 6-OHDA by regulating the ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways. Citronellol can induce necroptosis in human lung cancer cells through the TNF-α pathway and accumulation of ROS. Citronellol can reduce the levels of LC-3 and p62 to regulate the autophagy pathway, inhibit oxidative stress and neuroinflammation, and thus have neuroprotective effects on Parkinson's rats. Citronellol exhibits anti-fungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis[2][4][6][7].

[220687-53-6]

C10H14D6O

162.3

[2H]C([2H])([2H])/C(C([2H])([2H])[2H])=C/CCC(C)CCO

Isotope-Labeled Compounds; Reactive Oxygen Species (ROS)

10 mM in DMSO

Room temperature