CL2E-SN38 (TFA)

CL2E-SN-38 TFA, a highly releasable and structurally stable antibody-SN-38-conjugate, is a part of the antibody drug conjugate (ADC) . SN-38, the active metabolite of Irinotecan from camptothecins, is an Topoisomerase I inhibitor[1].

C89H117F3N14O26

1855.95

O=C1N(C2)C(C(C2=C(C3=C4)CC)=NC3=CC=C4OC(N(C)CCN(C)C(OCC(C=C5)=CC=C5NC([C@H](CCCCN)NC([C@@H](NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN(N=N6)C=C6CNC(C(CC7)CCC7CN(C8=O)C(C=C8)=O)=O)=O)=O)CC9=CC=CC=C9)=O)=O)=O)=O)=CC([C@](O)%10CC)=C1COC%10=O.O=C(O)C(F)(F)F

Drug-Linker Conjugates for ADC

99.51

DMSO : 100 mg/mL (ultrasonic)

4°C (Powder, protect from light, stored under nitrogen)

Room Temperature