The CLEC5A/MDL-1 protein positively regulates osteoclastogenesis and regulates inflammatory responses. It acts as a critical macrophage receptor for dengue virus serotypes 1-4, triggering signaling through TYROBP phosphorylation. This interaction stimulates the release of pro-inflammatory cytokines without viral entry. CLEC5A/MDL-1 Protein, Human (HEK293, Fc) is the recombinant human-derived CLEC5A/MDL-1 protein, expressed by HEK293 , with N-hFc labeled tag.
Molecular Formula
23601 (Gene_ID) Q9NY25 (Y26-K188) (Accession)
Purity
95
Storage Conditions
Stored at -20°C for 2 years
Shipping Conditions
Room temperature in continental US; may vary elsewhere.