Cletoquine-d4 [CAS 1854126-47-8]

Cletoquine-d4 is deuterium labeled Cletoquine. Cletoquine (Desethylhydroxychloroquine) is a major active metabolite of Hydroxychloroquine. Cletoquine is produced in the liver by CYP2D6, CYP3A4, CYP3A5, and CYP2C8 isoenzymes. Cletoquine is also a Chloroquine derivative and has the ability to against the chikungunya virus (CHIKV) . Cletoquine has antimalarial effects and has the potential for autoimmune diseases treatment[1][2].

[1854126-47-8]

C16H18D4ClN3O

311.84

[2H]C([2H])(NCCCC(NC1=CC=NC2=CC(Cl)=CC=C12)C)C([2H])(O)[2H]

CHIKV; Influenza Virus; Isotope-Labeled Compounds; Parasite

Plasmodium

10 mM in DMSO

Room temperature