CLK1/4-IN-1 [CAS 3029431-90-8]

CLK1/4-IN-1 (compound 31) is a potent and selective Clk1 and Clk4 inhibitor with an IC50 value of 9.7 nM and 6.6 nM, respectively. CLK1/4-IN-1 has growth inhibitory activities against T24 cancer cells with GI50 of 1.1 μM. CLK1/4-IN-1 can be used for researching anticancer[1].

[3029431-90-8]

C18H14ClNO4S

375.83

O=C(NC(C1=C(C=CC(Cl)=C1)OC)=O)C2=CC3=CC(OC)=CC=C3S2

CDK

CLK

10 mM in DMSO

Room temperature