Name: CLZ-8 [CAS 678158-55-9]
Brand: QuantiMol
SKU: QM-0140599-01
Price: 200.66 GBP
Availability: InStock

Product Details

Description
CLZ-8 (Compound 8) is an orally active Mcl-1-PUMA interface inhibitor, with a Ki of 0.3 μM. CLZ-8 exhibits dual activity on reduce PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis in cancer cells[1].
CAS Number
[678158-55-9]
Molecular Formula
C22H23N3O2S
Molecular Weight
393.5
Smiles
O=C1N=C(N2CCN(CCO)CC2)S/C1=C\C3=CC=C(C4=CC=CC=C4)C=C3
Target
Apoptosis; Bcl-2 Family
Isoform
Mcl-1
Purity
99.14
Solubility
DMSO : 50 mg/mL (ultrasonic)
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Shipping Conditions
Room Temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0140599-01	5 mgQM-0140599-01 £200.66/ea	£0.00	Quantity	£200.66/ea	£0.00

10 mM - 1 mLQM-0140599-02	10 mM - 1 mLQM-0140599-02 £215.24/ea	£0.00	Quantity	£215.24/ea	£0.00

10 mgQM-0140599-03	10 mgQM-0140599-03 £301.50/ea	£0.00	Quantity	£301.50/ea	£0.00

25 mgQM-0140599-04	25 mgQM-0140599-04 £551.80/ea	£0.00	Quantity	£551.80/ea	£0.00

50 mgQM-0140599-05	50 mgQM-0140599-05 £853.12/ea	£0.00	Quantity	£853.12/ea	£0.00

100 mgQM-0140599-06	100 mgQM-0140599-06 £1,305.10/ea	£0.00	Quantity	£1,305.10/ea	£0.00

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CLZ-8 [CAS 678158-55-9]

CLZ-8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.