CMPDA [CAS 380607-77-2]
CMPDA [CAS 380607-77-2]
SKU:QM-0141417-01
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Product Details
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Description
CMPDA is a positive allosteric modulator of AMPA receptors with EC50s of 45.4 ± 4.2 nM/63.4 ± 5.6 nM for GluA2i/GluA2o receptor. IC50 value: 45.4 ± 4.2 nM/63.4 ± 5.6 nM (GluA2i/GluA2o) [1] Target: AMPAR modulator CMPDA was nearly equipotent at modulating the two isoforms of GluA2 receptors, whereas CMPDB displayed a modest preference for the flip splice variant. Similar to CX614, CMPDA slowed the rate of deactivation of GluA2o receptors approximately 2-fold but had no effect on GluA2i receptor deactivation [1].
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CAS Number
[380607-77-2]
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Molecular Formula
C16H28N2O4S2
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Molecular Weight
376.53
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Smiles
O=S(NCCC1=CC=C(CCNS(=O)(C(C)C)=O)C=C1)(C(C)C)=O
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Target
IGluR
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Isoform
AMPA Receptor
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Concentration
10mM
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Purity
99.31
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Solubility
DMSO : ≥ 100 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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CMPDA [CAS 380607-77-2]
CMPDA is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.