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SKU:QM-0138366-01
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COH000 is an allosteric, covalent and irreversible inhibitor of ubiquitin-like 1-activating enzyme (SUMO-activating enzyme) (E1), with an IC50 of 0.2 μM for SUMOylation in vitro[1].
[1534358-79-6]
C25H25NO5
419.47
CC(C=C1)=CC=C1C[C@@H](NC2=CC=CC=C2)[C@]34C(C(OC)=O)=C(C(OC)=O)[C@@H](O4)C=C3
E1/E2/E3 Enzyme
98
DMSO : 35.71 mg/mL (ultrasonic)
-20°C, 3 years; 4°C, 2 years (Powder)
Room Temperature
H302, H315, H319, H335
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COH000 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.