Corr4A [CAS 421580-53-2]

Corr4A is a chemical corrector, which can be used for cystic fibrosis. Corr4A interacts directly with the cystic fibrosis transmembrane conductance regulator (CFTR) or affects indirectly its folding process. Corr4A increases the expression of CFTR ΔF508 on the cell surface, thereby improving its transport to the plasma membrane and increasing the stability of the rescued mutant protein[1].

[421580-53-2]

C21H17ClN4O2S2

456.97

O=C(NC1=NC(C)=C(C2=CSC(NC3=CC(Cl)=CC=C3OC)=N2)S1)C4=CC=CC=C4

CFTR

98.36

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature