COX-2/15-LOX-IN-3

Size 1 Each

SKU:QM-0071603

Price on request

Quote Datasheet SDS COA

Product Details

Description
COX-2/15-LOX-IN-3 (compound 5k) is a dual inhibitor of COX-2/15-LOX with IC50s of 0.075 μM and 1.97 μM, respectively. COX-2/15-LOX-IN-3 can inhibit LPS-induced cell production of promoting cytokines (IL-6, ROS, and NO), with specific anti-inflammatory activity[1].
Molecular Formula
C25H24FN3O3S
Molecular Weight
465.54
Smiles
COC1=C(OC)C(OC)=CC(C2=NC3=C(C(CCCC4)=C4S3)C(NC5=CC=C(F)C=C5)=N2)=C1
Target
COX; Lipoxygenase
Solubility
10 mM in DMSO
Shipping Conditions
Room temperature

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COX-2/15-LOX-IN-3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.