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COX-2/15-LOX/mPGES1-IN-1

COX-2/15-LOX/mPGES1-IN-1

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QM-0073529

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Product Details

  • Description

    COX-2/15-LOX/mPGES1-IN-1 (Compound 2c) is an inhibitor of COX-2, 15-LOX, and mPGES-1 enzymes with IC50 values of 0.057, 2.39, and 2.8 μM, respectively. COX-2/15-LOX/mPGES1-IN-1 possesses anti-inflammatory activity and can inhibit rat paw edema in vivo experiments[1].

  • Molecular Formula

    C19H16N2O5

  • Molecular Weight

    352.34

  • Smiles

    O=C(N/N=C/C1=COC2=C(C=CC(OC)=C2)C1=O)OCC3=CC=CC=C3

  • Target

    COX; Lipoxygenase

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature
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1 EachQM-0073529
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