COX-2-IN-61

COX-2-IN-61 is an orally active COX-2 inhibitor with an IC50 of 22 µM, also inhibits COX-1 with an IC50 of 43 µM. COX-2-IN-61 exhibits anti-inflammation effects in a Carrageenan induced rat paw edema model, with promising safety profiles. COX-2-IN-61 can be used for the research of inflammation[1].

C15H13N3O3S2

347.41

O=S(C1=CC=C(N2N=C(C3=CC=CS3)C(/C=N/O)=C2)C=C1)(C)=O

COX

COX-1; COX-2

Room temperature