CP-470711 [CAS 300548-99-6]

CP-470711 is an orally active and potent and selective sorbitol dehydrogenase (SDH) inhibitor with an IC50=10 nM for human SDH and IC50=17 nM for rat SDH. CP-470711 is promising for research of chronic complications related to type 2 diabetes mellitus, such as neuropathy and nephropathy[1].

[300548-99-6]

C18H26N6O2

358.44

C[C@@H]1N(C2=NC([C@H](O)C)=NC=C2)[C@@H](CN(C3=NC([C@H](O)C)=NC=C3)C1)C

Aldehyde Dehydrogenase (ALDH)

Room temperature