CPD-1224 [CAS 2891620-68-9]

CPD-1224 is an orally effective ALK inhibitor, a derivative of an ALK inhibitor that connects to the cereblon ligand. CPD-1224 targets the EML4-ALK oncogenic fusion protein and degrades both ALK and the mutant forms L1196M/G1202R. CPD-1224 can slow down tumor growth[1].

[2891620-68-9]

C43H47ClN8O7S

855.4

ClC1=CN=C(NC2=C(OC)C=C(C3CCN(CC4CN(C5=CC=C6C(C(N(C7CCC(NC7=O)=O)C6=O)=O)=C5)C4)CC3)C(C)=C2)N=C1NC8=C(S(C(C)C)(=O)=O)C=CC=C8

Anaplastic lymphoma kinase (ALK)

99.83

DMSO : 14.29 mg/mL (ultrasonic; warming; heat to 160°C)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature