CPS-11 [CAS 145945-21-7]

CPS-11 (N- (Hydroxymethyl) thalidomide) a Thalidomide analogue, is a potent anti-cancer agent. CPS-11 inhibits NF-κB, activates NFAT, and repress cytokine expression through elevated ROS. CPS-11 exhibits a wider activity spectrum and higher potency against MM (multiple myeloma) cell lines[1][2][3].

[145945-21-7]

C14H12N2O5

288.26

O=C1N(C(C2=C1C=CC=C2)=O)C(C(N3CO)=O)CCC3=O

NF-κB; Nuclear Factor of activated T Cells (NFAT) ; Reactive Oxygen Species (ROS)

99.39

4°C (Powder, protect from light)

Room Temperature