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CRM1-IN-1
CRM1-IN-1
SKU:QM-0072140
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Quantity
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Product Details
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Description
CRM1-IN-1 (Compound KL1) is a noncovalent CRM1 inhibitor. CRM1-IN-1 induces nuclear CRM1 degradation (IC50: 0.27 μM) . CRM1-IN-1 inhibits CRM1-mediated nuclear export and cell proliferation, and triggers apoptosis in colorectal cancer cells[1].
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Molecular Formula
C29H48N2O5
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Molecular Weight
504.7
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Smiles
[H][C@]1([C@H](N)/C=C/C=C(C)/C[C@@H](C)/C=C(\C=C\[C@@]([H])(C[C@H](N)CC(OC)=O)O)C)O[C@@]([H])(/C=C/C)[C@@H](C)[C@@H](O)C1
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Target
CRM1
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CRM1-IN-1
CRM1-IN-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.