Cromolyn [CAS 16110-51-3]

Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects[1][2][3][4][5].

[16110-51-3]

C23H16O11

468.37

OC(COC1=C2C(C=C(C(O)=O)OC2=CC=C1)=O)COC3=C4C(C=C(C(O)=O)OC4=CC=C3)=O

Amyloid-β; GSK-3; NF-κB

99.91

DMSO : 175 mg/mL (ultrasonic)

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature

H315, H319, H335

H315, H319, H335