CT-996 [CAS 2810808-95-6]

CT-996 is an orally active GLP-1RA agonist, with an EC50 of 0.49 nM. CT-996 reduces the β-arrestin recruitment and GLP-1R internalization. CT-996 suppresses postprandial blood glucose following a mixed meal tolerance test (MMTT) in mice expressing the human GLP-1 receptor and enhances glucose stimulated insulin secretion (GSIS) during an intravenous glucose challenge in obese monkeys. CT-996 can be used for the study of type 2 diabetes (T2D) and obesity[1][2].

[2810808-95-6]

C30H31F2N5O5

579.59

C[C@@H](C[C@H](CC1)OC2=NC(COC3=C(C=C(C=C3)F)F)=NC=C2)N1CC(N(C4=C5)C[C@@H]6CCO6)=NC4=CC=C5C(O)=O

Arrestin; GLP Receptor

99.97

DMSO : ≥ 100 mg/mL

4°C (Powder, protect from light)

Room Temperature