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CU-115 [CAS 2471982-20-2]

CU-115 [CAS 2471982-20-2]

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SKU:QM-0143776-01

£275.99 GBP
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  • Description

    CU-115 is a potent TLR8 antagonist (IC50=1.04 μM), and shows selective for TLR8 over TLR7 (IC50=>50 μM) . CU-115 decreases TNF-α and IL-1β production activated by R-848 in THP-1 cells[1].

  • CAS Number

    [2471982-20-2]

  • Molecular Formula

    C21H11F7INO2

  • Molecular Weight

    569.21

  • Smiles

    O=C(NC1=CC=C(OC2=CC(C(F)(F)F)=CC(C(F)(F)F)=C2)C=C1)C3=C(I)C=CC=C3F

  • Target

    Toll-like Receptor (TLR)

  • Isoform

    TLR7; TLR8

  • Purity

    99.63

  • Solubility

    DMSO : 100 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

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Variant Variant total Quantity Price Variant total
5 mgQM-0143776-01
5 mgQM-0143776-01
£275.99/ea
£0.00
£275.99/ea £0.00
10 mM - 1 mLQM-0143776-02
10 mM - 1 mLQM-0143776-02
£331.88/ea
£0.00
£331.88/ea £0.00
10 mgQM-0143776-03
10 mgQM-0143776-03
£414.50/ea
£0.00
£414.50/ea £0.00
25 mgQM-0143776-04
25 mgQM-0143776-04
£678.15/ea
£0.00
£678.15/ea £0.00
50 mgQM-0143776-05
50 mgQM-0143776-05
£928.45/ea
£0.00
£928.45/ea £0.00
100 mgQM-0143776-06
100 mgQM-0143776-06
£1,279.58/ea
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£1,279.58/ea £0.00

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CU-115 [CAS 2471982-20-2]

CU-115 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.