Cu (II) GTSM, a cell-permeable Cu-complex, significantly inhibits GSK3β. Cu (II) GTSM inhibits Amyloid-β oligomers (AβOs) and decreases tau phosphorylation. Cu (II) GTSM also decreases the abundance of Amyloid-β trimers. Cu (II) GTSM is a potential anticancer and antimicrobial agent[1][2].
CAS Number
[68341-14-0]
Molecular Formula
C6H10CuN6S2
Molecular Weight
293.86
Smiles
CNC1=N[N]2=CC=[N]3N=C(NC)[S-][Cu+2]23[S-]1
Target
Amyloid-β; GSK-3
Isoform
GSK-3β
Purity
95
Solubility
DMSO : 2 mg/mL (ultrasonic; warming; adjust pH to 2 with 1 M HCL; heat to 60°C)