Cyclic ADP-ribose (ammonium)
Cyclic ADP-ribose (ammonium)
SKU:QM-0089253
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Product Details
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Description
Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent second messenger for calcium mobilization that is synthesized from NAD+ by an ADP-ribosyl cyclase. Cyclic ADP-ribose ammonium increases cytosolic calcium mainly by Ryanodine receptor-mediated release from endoplasmic reticulum and also by extracellular influx through the opening of TRPM2 channels[1][2][3].
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Molecular Formula
C15H21N5O13P2.xNH3
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Smiles
O[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N(C=N3)[C@@H]([C@H](O)[C@@H]4O)O[C@@H]4CO5)=N)O[C@@H]1COP(OP5(O)=O)(O)=O.N.[x]
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Target
Calcium Channel; Endogenous Metabolite; TRP Channel
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Purity
99.9
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Hazard Statement
H315, H319, H335
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Precautions
H315, H319, H335
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Cyclic ADP-ribose (ammonium)
Cyclic ADP-ribose (ammonium) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.