Cyclo (L-Phe-L-Pro) [CAS 3705-26-8]

Cyclo (L-Phe-L-Pro), isolated from Pseudomonas fluorescens and Pseudomonas alcaligenes cell-free culture supernatants is an antifungal cyclic dipeptide[1]. Cyclo (L-Phe-L-Pro) inhibits IFN-β production by interfering with retinoic-acid-inducible gene-I (RIG-I) activation[2]. Cyclo (L-Phe-L-Pro) exhibits free-radical scavenging activity with the IC50 of 24 µM in the DPPH assay[3].

[3705-26-8]

C14H16N2O2

244.29

O=C(N[C@H]1CC2=CC=CC=C2)[C@@](CCC3)([H])N3C1=O

Bacterial; Fungal; IFNAR; Reactive Oxygen Species (ROS)

99.91

DMSO : 250 mg/mL (ultrasonic)

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Blue Ice

H301, H311, H331

H301, H311, H331