Cyclocreatine (Standard) [CAS 35404-50-3]
Cyclocreatine (Standard) [CAS 35404-50-3]
SKU:QM-0048685-01
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Product Details
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Description
Cyclocreatine, a creatine analogue, acts as a brain-penetrant and potent bioenergetic protective agent by providing high levels of ATP. Cyclocreatine can be phosphorylated and dephosphorylated by creatine kinases. Cyclocreatine suppresses creatine metabolism ameliorating the cognitive, autistic and epileptic phenotype in a mouse model of creatine transporter defciency. Cyclocreatine protects against ischemic injury and enhances cardiac recovery during early reperfusion in dogs and rats. Cyclocreatine decreases plaque-adjacent neuronal dystrophy in TREM2-deficient mice with amyloid-β pathology. Cyclocreatine is proming for research of ischemic heart disease, cardiovascular diseases, Alzheimer’s disease and other neurodegenerative diseases associated with microglial dysfunction, prostate cancer[1][2][3][4][5].
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CAS Number
[35404-50-3]
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Molecular Formula
C5H9N3O2
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Molecular Weight
143.15
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Smiles
O=C(O)CN1CCNC1=N
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Target
ATP Synthase
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Shipping Conditions
Room temperature
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Cyclocreatine (Standard) [CAS 35404-50-3]
Cyclocreatine (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.