Cyclopentenylcytosine [CAS 90597-22-1]

Cyclopentenylcytosine (CPEC), a carbocyclic nucleoside analog of cytosine, is a potent inhibitor of CTP synthetase and causes depletion of CTP and dCTP pools. Cyclopentenylcytosine shows broad-spectrum (both DNA and RNA viruses) antiviral activity. Cyclopentenyl cytosine increases Gemcitabine radiosensitisation in human pancreatic cancer cells. Cyclopentenylcytosine shows effective antiviral activity in the Ad5/NZW rabbit ocular replication model and shows anti-tumor activity in various tumor xenografts model. Cyclopentenylcytosine can be used for the study of infection and cancer[1][2][3][4].

[90597-22-1]

C10H13N3O4

239.23

O[C@H]1[C@H](N2C(N=C(N)C=C2)=O)C=C(CO)[C@H]1O

Apoptosis; DNA/RNA Synthesis; HSV; Influenza Virus; Necroptosis; Nucleoside Antimetabolite/Analog

99.76

-20°C, 3 years; 4°C, 2 years (Powder)

Room Temperature