CYP51-IN-25

CYP51-IN-25 is a orally active broad spectrum antifungal agent with the MIC80 of 0.00625-0.05 μg/mL. is a CYP51-IN-25 is a deuterated compound with antibiotic properties. CYP51-IN-25 can inhibit the fungal CYP51 enzyme, block ergosterol synthesis, and disrupt cell membrane integrity. CYP51-IN-25 can be used for research on fungal infections[1].

C27H22D3F5N4O2

535.52

FC1=CC=C([C@]([C@H](C)N(C([2H])([2H])[2H])CC2=CC=C(C3=CC=C(OC(F)(F)F)C=C3)C=C2)(O)CN4C=NC=N4)C(F)=C1

Cytochrome P450; Fungal; Isotope-Labeled Compounds

Room temperature