CYP51/PD-L1-IN-4 [CAS 3032391-34-4]

CYP51/PD-L1-IN-4 (compound 14a-2) is a potent dual-target (CYP51/PD-L1) inhibitor, with IC50 values of 0.17 and 0.021 μM, respectively. CYP51/PD-L1-IN-4 exhibits excellent antifungal and antidrug-resistant fungal activity in vitro. CYP51/PD-L1-IN-4 can be used for fungal infections research[1].

[3032391-34-4]

C28H30N4O3

470.56

CC1=C(C2=CC=CC=C2)C=CC=C1COC3=CC(CN[C@@H](C(OCC)=O)CN4C=NC=N4)=CC=C3

Cytochrome P450; PD-1/PD-L1

CYP51

10 mM in DMSO

Room temperature