CypB-IN-1

CypB-IN-1 (Compound 11) is an inhibitor of cyclophilin B (cyclophilin B) with a Kd value of 12 nM. CypB-IN-1 can be applied to the research field of metabolic dysfunction-associated steatohepatitis (MASH) and the liver fibrosis diseases resulting from it[1].

C24H29ClN8O2S

529.06

O=C(NCC(N1[C@@H](C2=CC=CC=C2SC)CCC1)=O)N(CC3=CC=C(N)C(Cl)=C3)CC4=NN(C)N=N4

Cyclophilin

Cyclophilin B

Room temperature