D-Isoleucine [CAS 319-78-8]
D-Isoleucine [CAS 319-78-8]
SKU:QM-0118037-01
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Product Details
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Description
D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM) . D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia) . D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2].
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CAS Number
[319-78-8]
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Molecular Formula
C6H13NO2
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Molecular Weight
131.18
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Smiles
CC[C@@H](C)[C@@H](N)C(O)=O
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Target
ASCT
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Purity
99.83
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Solubility
H2O : 5.56 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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D-Isoleucine [CAS 319-78-8]
D-Isoleucine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.