[DAla4] Substance P (4-11) [CAS 81381-50-2]

[DAla4] Substance P (4-11) is an analog of Substance P that inhibits the binding of 125I-Bolton Hunter-conjugated Eledoisin (HY-P0006) (IC50 of 0.5 μM) and 125I-Bolton Hunter-conjugated Substance P (IC50 of 0.15 μM) to rat brain cortex membranes[1].

[81381-50-2]

C44H65N11O10S

940.12

CSCC[C@@H](C(N)=O)NC([C@H](CC(C)C)NC(CNC([C@H](CC1=CC=CC=C1)NC([C@@H](NC([C@H](CCC(N)=O)NC([C@H](CCC(N)=O)NC([C@H](N)C)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O

Neurokinin Receptor

10 mM in DMSO

Room temperature