Damulin B [CAS 1202868-75-4]

Damulin B is a dammarane-type saponin found in Gynostemma pentaphyllum. Damulin B can inhibit cancer cell apoptosis, decrease mitochondrial membrane potential, inhibit ROS production and cause G0/G1 phase arrest. Damulin B can prevent Cisplatin -induced acute kidney injury and induce hair growth. Damulin B shows anti-inflammation anti-diabetic and anti-obesity effect. Damulin B can be used for the researches of cancer, inflammation, metabolic disease, such as lung cancer, osteoarthritis and diabetes[1][2][3][4][5][6].

[1202868-75-4]

C42H70O13

783

O[C@@H]([C@@H]([C@@H](CO)O1)O)[C@@H](O[C@H]2[C@@H]([C@H]([C@@H]([C@@H](CO)O2)O)O)O)[C@@H]1O[C@H]3[C@H](O)C[C@]4(C)[C@@]5([H])C[C@@H](O)[C@@H]6[C@@H](C(CC/C=C(C)\C)=C)CC[C@@]6(C)[C@@](C)5CC[C@@]4([H])C3(C)C

Apoptosis; Bcl-2 Family; CDK; Interleukin Related; MDM-2/p53; MMP; Reactive Oxygen Species (ROS)

Bcl-2; CDK4; CDK6; MMP-2; MMP-9

97.89

DMSO : ≥ 50 mg/mL

4°C (Powder, protect from light)

Room Temperature