Danvatirsen sodium is an antisense oligonucleotide targeting STAT3 with potential antitumor activity. Danvatirsen sodium binds to STAT3 mRNA, thereby inhibiting translation of the transcript. Suppression of STAT3 expression induces tumor cell apoptosis and decreases tumor cell growth.
Smiles
[Danvatirsen(sodium)]
Target
Apoptosis; STAT
Purity
99.46
Solubility
10 mM in H2O
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)