Darifenacin-d4 [CAS 1095598-84-7]

Darifenacin-d4 is the deuterium labeled Darifenacin[1]. Darifenacin (UK88525) is a selective M3 muscarinic receptor antagonist with pKi of 8.9. IC50 value: 8.9 (pKi) [2].

[1095598-84-7]

C28H26D4N2O2

430.57

NC(C(C1=CC=CC=C1)(C2=CC=CC=C2)[C@H]3CN(CC3)C([2H])([2H])C([2H])([2H])C4=CC=C(OCC5)C5=C4)=O

MAChR

10 mM in DMSO

Room temperature