Dasatinib (GMP) [CAS 302962-49-8]
Dasatinib (GMP) [CAS 302962-49-8]
SKU:QM-0081569
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Product Details
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Description
Dasatinib (BMS-354825) (GMP) is a GMP-grade Dasatinib (HY-10181) . GMP-grade small molecules can be used as adjuvant agents in cell therapy. Dasatinib (BMS-354825) is an orally active, ATP-competitive, dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Ki values for Src and Bcr-Abl are 16 pM and 30 pM, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50 values of less than 1.0 nM and 0.5 nM, respectively. Dasatinib also induces apoptosis and autophagy[1].
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CAS Number
[302962-49-8]
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Molecular Formula
C22H26ClN7O2S
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Molecular Weight
488.01
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Smiles
O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C
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Target
Apoptosis; Autophagy; Bcr-Abl; Src
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Shipping Conditions
Room temperature
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Hazard Statement
H315-H318-H351-H361-H372-H401-H410
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Precautions
P260-P264-P270-P273-P280-P302+P352-P362-P391-P405-P501
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Dasatinib (GMP) [CAS 302962-49-8]
Dasatinib (GMP) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.