DBCO-PEG4-SS-TCO

DBCO-PEG4-SS-TCO is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-PEG4-SS-TCO is a click chemistry reagent, it contains a TCO group that can undergo an inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

C43H58N4O9S2

839.07

O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCC(NCCSSCCNC(O[C@H]4CCC/C=C/CC4)=O)=O)=O

ADC Linker

Cleavable Linker; Disulfide Cleavable Linker

98.78

10 mM in DMSO

-20°C, 3 years (Powder)

Blue Ice

H302, H315, H319, H335

H302, H315, H319, H335