DBCO-PEG4-Val-Ala-PAB [CAS 2348405-92-3]

DBCO-PEG4-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala linkers can be cleaved by Cathepsin B. The DBCO groups is commonly used for Click Chemistry reactions. PEG spacer improves the compound's aqueous solubility.

[2348405-92-3]

C45H57N5O10

827.96

CC([C@@H](C(N[C@H](C(NC1=CC=C(C=C1)CO)=O)C)=O)NC(CCOCCOCCOCCOCCNC(CCC(N2CC3=C(C#CC4=C2C=CC=C4)C=CC=C3)=O)=O)=O)C

ADC Linker

Room temperature