DBET23 [CAS 1957234-83-1]

DBET23 is a highly effective and selective PROTAC BRD4 degrader with a DC50/5h of ~ 50 nM for BRD4BD1 protein[1].

[1957234-83-1]

C43H45ClN8O9S

885.38

O=C(OC)C[C@H]1C2=NN=C(C)N2C3=C(C(C)=C(C(NCCCCCCCCNC(COC4=CC=CC(C(N5C(CC6)C(NC6=O)=O)=O)=C4C5=O)=O)=O)S3)C(C7=CC=C(Cl)C=C7)=N1

Epigenetic Reader Domain; PROTACs

95.83

DMSO : 110 mg/mL (ultrasonic; warming; heat to 60°C)

-20°C (Powder, sealed storage, away from moisture and light)

Blue Ice