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SKU:QM-0072556-01
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DBr-1 is a potent BRD9 PROTAC degrader (KD: 13 nM). DBr-1 can overcome intrinsic resistance to VHL-degrader. Blue: DCAF1 binder , Black: linker, Pink: BRD9/BRD7 bromodomains inhibitor (HY-100352).
C55H68ClN9O5
970.64
COC1=C(C(C2=C3C=NC=C2)=CN(C)C3=O)C=C(OC)C(CN4CCC(OCCCCCC(N5CCN(C6=CC=C7C(N=C(C8(C9=CC=C(Cl)C=C9)CCCCC8)N=C7NCCN)=C6)CC5)=O)CC4)=C1
Epigenetic Reader Domain; PROTACs
98.87
DMSO : 100 mg/mL (ultrasonic)
-20°C, 3 years (Powder)
Blue Ice
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DBr-1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.