DC1 [CAS 169901-27-3]

DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin. DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer.

[169901-27-3]

C34H28ClN5O4S

638.14

O=C(C(N1)=CC2=C1C=CC(NC(CCS)=O)=C2)NC3=CC4=C(NC(C(N5C[C@@H](CCl)C6=C5C=C(O)C7=CC=CC=C67)=O)=C4)C=C3

ADC Payload; DNA Alkylator/Crosslinker

Duocarmycins

10 mM in DMSO

Room temperature